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RTFS Hollow Fiber Filter

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RTFS are repeatedly steam-sterilizable hollow fiber filter products developed by GVS. Engineered for steam sterilization conditions in pharmaceutical processes, they balance easy operation and process stability, fully meeting biopharmaceutical production requirements for hygiene standards and operational efficiency.


The filter housing is manufactured from medical-grade Polysulfone (PSU), featuring outstanding mechanical strength, temperature resistance and anti-creep performance. It reliably withstands high-temperature, high-pressure impacts and thermal cycling stress during in-situ steam sterilization, maintaining structural integrity after repeated long-term sterilization cycles.


Mounting dimensions and interface specifications are fully compatible with mainstream equivalent products available on the market. Matching O-rings for stainless steel housings are supplied to support direct replacement and lower customers’ process adaptation costs.


The core filter membrane adopts modified Polyethersulfone (mPES). Precisely controlled membrane fabrication processes guarantee consistent filtration performance and structural stability. Rigorous verification confirms that key indicators including filtration performance and physicochemical properties remain highly consistent before and after steam sterilization, delivering excellent

process reproducibility.

Ultrafiltration (UF) Series: Rating ranges from 1 kDa ~ 750 kDa; optional fiber inner diameters: 1.0 mm

Microfiltration (MF) Series: Rating from 0.1 μm ~ 0.5 μm; optional fiber inner diameters: 0.8 mm / 1.0 mm


Applications

• Cell perfusion culture

• Liposome filtration for small-molecule pharmaceuticals


Material of Constructions

• Membrane Material: PES(modified)

• Housing: PSU

• Potting Material: Polyurethane

• O-Ring: Silicone

• Netting: Polypropylene

• Antifreeze/Bacteriostat: Glycerin/NaOH


Max.Inlet Pressure

0~45°C

3bar
45°C~60°C 1.5bar
60°C~80°C 0.5bar
Max.TMP

0~45°C 

2bar
45°C~60°C1bar
60°C~80°C0.5bar

Max.Sterilization

Temperature

125°C
pH Range1-14

* For product customization and selection, please consult the GVS technical team first.